Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to fully realizing the potential of mRNA vaccines. Pre-clinical and clinical studies have demonstrat...

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Bibliographic Details
Main Authors: Kimberly J. Hassett, Kerry E. Benenato, Eric Jacquinet, Aisha Lee, Angela Woods, Olga Yuzhakov, Sunny Himansu, Jessica Deterling, Benjamin M. Geilich, Tatiana Ketova, Cosmin Mihai, Andy Lynn, Iain McFadyen, Melissa J. Moore, Joseph J. Senn, Matthew G. Stanton, Örn Almarsson, Giuseppe Ciaramella, Luis A. Brito
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119300174

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http://www.sciencedirect.com/science/article/pii/S2162253119300174

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