Behavioral and Neurochemical Phenotyping of Mice Incapable of Homer1a Induction

Behavioral and Neurochemical Phenotyping of Mice Incapable of Homer1a Induction

Immediate early and constitutively expressed products of the Homer1 gene regulate the functional assembly of post-synaptic density proteins at glutamatergic synapses to influence excitatory neurotransmission and synaptic plasticity. Earlier studies of Homer1 gene knock-out (KO) mice indicated active...

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Bibliographic Details
Main Authors: Michael C. Datko, Jia-Hua Hu, Melanie Williams, Cindy M. Reyes, Kevin D. Lominac, Georg von Jonquieres, Matthias Klugmann, Paul F. Worley, Karen K. Szumlinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Homer1a
cocaine
glutamate
dopamine
nucleus accumbens
anxiety
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00208/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00208/full

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