Role of chaperone-mediated autophagy in the pathophysiology including pulmonary disorders

Abstract Autophagy is a highly conserved mechanism of delivering cytoplasmic components for lysosomal degradation. Among the three major autophagic pathways, chaperone-mediated autophagy (CMA) is primarily characterized by its selective nature of protein degradation, which is mediated by heat shock...

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Bibliographic Details
Main Authors: Yusuke Hosaka, Jun Araya, Yu Fujita, Kazuyoshi Kuwano
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Inflammation and Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s41232-021-00180-9