Effect of Function‐Enhanced Mesenchymal Stem Cells Infected With Decorin‐Expressing Adenovirus on Hepatic Fibrosis

Effect of Function‐Enhanced Mesenchymal Stem Cells Infected With Decorin‐Expressing Adenovirus on Hepatic Fibrosis

Bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are known to have an antifibrotic effect and could be used as vehicles for targeted gene delivery. Decorin plays a protective role against fibrogenesis by modulating the degradation of the extracellular matrix. The aim of this study was to determi...

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Bibliographic Details
Main Authors: Yoon Ok Jang, Mee-Yon Cho, Chae-Ok Yun, Soon Koo Baik, Kyu-Sang Park, Seung-Kuy Cha, Sei Jin Chang, Moon Young Kim, Yoo Li Lim, Sang Ok Kwon
Format: Article
Language:English
Published: Wiley 2016-09-01
Series:Stem Cells Translational Medicine
Subjects:
Mesenchymal stem cell
Adenovirus
Gene therapy
Liver regeneration
Transforming growth factor‐β
Online Access:https://doi.org/10.5966/sctm.2015-0323

Internet

https://doi.org/10.5966/sctm.2015-0323

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