Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

To date, several families of peptide toxins specifically interacting with ion channels in scorpion venom have been described. One of these families comprise peptide toxins (called KTxs), known to modulate potassium channels. Thus far, 202 KTxs have been reported, belonging to several subfamilies of...

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Bibliographic Details
Main Authors: Caroline M. Cremonez, Mohitosh Maiti, Steve Peigneur, Juliana Silva Cassoli, Alexandre A. A. Dutra, Etienne Waelkens, Eveline Lescrinier, Piet Herdewijn, Maria Elena de Lima, Adriano M. C. Pimenta, Eliane C. Arantes, Jan Tytgat
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxins
Subjects:
Tityus serrulatus
scorpion toxin
Ts11
neurotoxin
NMR
protein structure
ICK fold
electrophysiology
potassium channel
Online Access:http://www.mdpi.com/2072-6651/8/10/288

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http://www.mdpi.com/2072-6651/8/10/288

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