An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelination

An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelination

Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, and results in the degradation of the myelin sheath. The study investigates the neuroprotective effects of krill oil (KO) on the cuprizone (CPZ)-induced demyelination of the MS mouse model. The results...

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Bibliographic Details
Main Authors: Ning Zhang, Li Jin, Chunhong Liu, Ruiyan Zhang, Hans-Christian Siebert, Yanhui Li, Gabriele Loers, Athanasios K. Petridis, Zhangyong Xia, Huijun Dong, Xuexing Zheng
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Functional Foods
Subjects:
Multiple sclerosis
Antarctic krill oil
Oxidative stress
Neuroinflammation
Microglia polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620305338

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http://www.sciencedirect.com/science/article/pii/S1756464620305338

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