Detection of motor changes in Huntington’s disease using dynamic causal modeling

Detection of motor changes in Huntington’s disease using dynamic causal modeling

Deficits in motor functioning are one of the hallmarks of Huntington’s disease (HD), a genetically caused neurodegenerative disorder. We applied functional magnetic resonance imaging (fMRI) and dynamic causal modeling (DCM) to assess changes that occur with disease progression in the neural circuitr...

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Bibliographic Details
Main Authors: Lora eMinkova, Elisa eScheller, Jessica ePeter, Ahmed eAbdulkadir, Christoph P. Kaller, Raymund A. Roos, Alexandra eDurr, Blair R. Leavitt, Sarah J. Tabrizi, Stefan eKlöppel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Human Neuroscience
Subjects:
fMRI
DCM
Cluster analysis
Huntington’s disease
Motor network
sequential finger tapping
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00634/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00634/full

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