Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.

ATP-dependent chromatin remodelers control DNA access for transcription, recombination, and other processes. Acf1 (also known as BAZ1A in mammals) is a defining subunit of the conserved ISWI-family chromatin remodelers ACF and CHRAC, first purified over 15 years ago from Drosophila melanogaster embr...

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Bibliographic Details
Main Authors: James A Dowdle, Monika Mehta, Elizabeth M Kass, Bao Q Vuong, Akiko Inagaki, Dieter Egli, Maria Jasin, Scott Keeney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3820798?pdf=render

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http://europepmc.org/articles/PMC3820798?pdf=render

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