Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-<i>b</i>]indole Derivative, Discovered as CK2 Inhibitor

Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-<i>b</i>]indole Derivative, Discovered as CK2 Inhibitor

Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive anticancer target. We previously described a prenyloxy-substituted indeno[1,2-<i>b</i>]indole (5-isopropyl-4-(3-methylbut-2-enyloxy)-5,6,7...

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Bibliographic Details
Main Authors: Ehab El-Awaad, Robin Birus, Christelle Marminon, Zouhair Bouaziz, Laurens Ballentin, Dagmar Aichele, Marc Le Borgne, Joachim Jose
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceuticals
Subjects:
CK2 inhibitor
indeno[1,2-<i>b</i>]indole
anticancer
pharmacokinetics
LC-MS
Online Access:https://www.mdpi.com/1424-8247/14/6/542

Internet

https://www.mdpi.com/1424-8247/14/6/542

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