Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system.

T cell epitope candidates are commonly identified using computational prediction tools in order to enable applications such as vaccine design, cancer neoantigen identification, development of diagnostics and removal of unwanted immune responses against protein therapeutics. Most T cell epitope predi...

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Bibliographic Details
Main Authors: Sinu Paul, Nathan P Croft, Anthony W Purcell, David C Tscharke, Alessandro Sette, Morten Nielsen, Bjoern Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007757