Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

Alzheimer's disease is a complex disease characterized by overlapping phenotypes with different neurodegenerative disorders. Oligomers are considered the most toxic species in amyloid pathologies. We examined human AD brain samples using an anti-oligomer antibody generated in our laboratory and...

Full description

Bibliographic Details
Main Authors: Marcos J. Guerrero-Muñoz, Diana L. Castillo-Carranza, Shashirekha Krishnamurthy, Adriana A. Paulucci-Holthauzen, Urmi Sengupta, Cristian A. Lasagna-Reeves, Yembur Ahmad, George R. Jackson, Rakez Kayed
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Neurobiology of Disease
Subjects:
Protein aggregation
Alzheimer's disease
Mixed proteinopathy
Aβ oligomers and cross seeding
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002393

Internet

http://www.sciencedirect.com/science/article/pii/S0969996114002393

Similar Items