Plant-derived peptides rubiscolin-6, soymorphin-6 and their c-terminal amide derivatives: Pharmacokinetic properties and biological activity

Plant-derived peptides rubiscolin-6, soymorphin-6 and their c-terminal amide derivatives: Pharmacokinetic properties and biological activity

The aim of this work is to investigate the pharmacokinetic properties, antinociceptive and antioxidant activities of rubiscolin-6, soymorphin-6 and their C-terminal amides; The four peptides were synthesized following Fmoc-SPPS strategy to give the final peptides in excellent overall yields and puri...

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Bibliographic Details
Main Authors: Azzurra Stefanucci, Marilisa Pia Dimmito, Giancarlo Tenore, Stefano Pieretti, Paola Minosi, Gokhan Zengin, Chiara Sturaro, Girolamo Calò, Ettore Novellino, Angelo Cichelli, Adriano Mollica
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Journal of Functional Foods
Subjects:
Opioid peptides
Rubiscolin-6
Soymorphin-6
Antinociception
Antioxidant activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620303789

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http://www.sciencedirect.com/science/article/pii/S1756464620303789

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