DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data

DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data

Abstract Background DNA methylation is an epigenetic modification that is studied at a single-base resolution with bisulfite treatment followed by high-throughput sequencing. After alignment of the sequence reads to a reference genome, methylation counts are analyzed to determine genomic regions tha...

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Bibliographic Details
Main Authors: John M. Gaspar, Ronald P. Hart
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
Bisulfite sequencing
CpG islands
Single-linkage clustering
Online Access:http://link.springer.com/article/10.1186/s12859-017-1909-0

Internet

http://link.springer.com/article/10.1186/s12859-017-1909-0

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