Therapeutic Effect of Rapamycin on Aortic Dissection in Mice

Therapeutic Effect of Rapamycin on Aortic Dissection in Mice

Aortic dissection (AD) is a serious clinical condition that is unpredictable and frequently results in fatal outcome. Although rapamycin, an inhibitor of mechanistic target of rapamycin (mTOR), has been reported to be effective in preventing aortopathies in mouse models, its mode of action has yet t...

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Bibliographic Details
Main Authors: Makiko Hayashi-Hori, Hiroki Aoki, Miho Matsukuma, Ryohei Majima, Yohei Hashimoto, Sohei Ito, Saki Hirakata, Norifumi Nishida, Aya Furusho, Satoko Ohno-Urabe, Yoshihiro Fukumoto
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
aortic dissection
mTOR
rapamycin
smooth muscle cells
inflammation
Online Access:https://www.mdpi.com/1422-0067/21/9/3341

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https://www.mdpi.com/1422-0067/21/9/3341

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