The footprint of the ageing stroma in older patients with breast cancer

The footprint of the ageing stroma in older patients with breast cancer

Abstract Background Tumours are not only composed of malignant cells but also consist of a stromal micro-environment, which has been shown to influence cancer cell behaviour. Because the ageing process induces accumulation of senescent cells in the body, this micro-environment is thought to be diffe...

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Bibliographic Details
Main Authors: Barbara Brouwers, Debora Fumagalli, Sylvain Brohee, Sigrid Hatse, Olivier Govaere, Giuseppe Floris, Kathleen Van den Eynde, Yacine Bareche, Patrick Schöffski, Ann Smeets, Patrick Neven, Diether Lambrechts, Christos Sotiriou, Hans Wildiers
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Stroma
Senescence
Senescence-associated secretory profile
Autophagy
Gene expression
Online Access:http://link.springer.com/article/10.1186/s13058-017-0871-0

Internet

http://link.springer.com/article/10.1186/s13058-017-0871-0

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