Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Release Syndrome Related to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivity Syndrome

Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Release Syndrome Related to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivity Syndrome

Currently, only a few reports exist on the cytokine release syndrome (CRS) as one of the severe immune-related adverse events (irAEs) induced by immune checkpoint inhibitors (ICIs). Notably, it is very rare that grade 4 CRS related to ICI therapy overlaps with the drug-induced hypersensitivity syndr...

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Bibliographic Details
Main Authors: Tetsuya Urasaki, Makiko Ono, Toshiaki Mochizuki, Koichi Takeda, Aya Nishizawa, Eri Fukagawa, Motohiro Fujiwara, Yoshinobu Komai, Shigehisa Kitano, Takeshi Yuasa, Junji Yonese, Shunji Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
immune checkpoint inhibitor
immune-related adverse event
trimethoprim/sulfamethoxazole
cytokine release syndrome
drug-induced hypersensitivity syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.681997/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.681997/full

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