Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

The mechanisms that mediate the effects of weight loss surgeries such as vertical sleeve gastrectomy (VSG) are incompletely understood. Here the authors show that intestinal FGF15 is necessary to improve glucose tolerance and to prevent the loss of muscle and bone mass after VSG, potentially via pro...

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Bibliographic Details
Main Authors: Nadejda Bozadjieva-Kramer, Jae Hoon Shin, Yikai Shao, Ruth Gutierrez-Aguilar, Ziru Li, Kristy M. Heppner, Samuel Chiang, Sara G. Vargo, Katrina Granger, Darleen A. Sandoval, Ormond A. MacDougald, Randy J. Seeley
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24914-y

Internet

https://doi.org/10.1038/s41467-021-24914-y

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