Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose

by Henriette Frikke-Schmidt, Peter Arvan, Randy J. Seeley, Corentin Cras-Méneur
Published 2021-01-01

High fat diet alters lactation outcomes: possible involvement of inflammatory and serotonergic pathways.

by Laura L Hernandez, Bernadette E Grayson, Ekta Yadav, Randy J Seeley, Nelson D Horseman
Published 2012-01-01

GLP-2 receptor signaling controls circulating bile acid levels but not glucose homeostasis in Gcgr−/− mice and is dispensable for the metabolic benefits ensuing after vertical slee...

by Anita Patel, Bernardo Yusta, Dianne Matthews, Maureen J. Charron, Randy J. Seeley, Daniel J. Drucker
Published 2018-10-01

GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice

by Henriette Frikke-Schmidt, Karin Hultman, Joseph W. Galaske, Sebastian B. Jørgensen, Martin G. Myers, Jr., Randy J. Seeley
Published 2019-03-01

Weight loss independent changes in adipose tissue macrophage and T cell populations after sleeve gastrectomy in mice

by Henriette Frikke-Schmidt, Brian F. Zamarron, Robert W. O'Rourke, Darleen A. Sandoval, Carey N. Lumeng, Randy J. Seeley
Published 2017-04-01

The anorectic effect of GLP-1 in rats is nutrient dependent.

by Darleen Sandoval, Jason G Barrera, Margaret A Stefater, Stephanie Sisley, Stephen C Woods, David D D'Alessio, Randy J Seeley
Published 2012-01-01

Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action

by Elodie M. Varin, Erin E. Mulvihill, Laurie L. Baggio, Jacqueline A. Koehler, Xiemin Cao, Randy J. Seeley, Daniel J. Drucker
Published 2019-06-01

High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney

by Kerstin Stemmer, Diego Perez-Tilve, Gayathri Ananthakrishnan, Anja Bort, Randy J. Seeley, Matthias H. Tschöp, Daniel R. Dietrich, Paul T. Pfluger
Published 2012-09-01

Electrical stimulation of renal nerves for modulating urine glucose excretion in rats

by Ahmad A. Jiman, Kavaljit H. Chhabra, Alfor G. Lewis, Paul S. Cederna, Randy J. Seeley, Malcolm J. Low, Tim M. Bruns
Published 2018-05-01

Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture

by Andrea V. Rozo, Daniella A. Babu, PoMan A. Suen, David N. Groff, Randy J. Seeley, Rebecca A. Simmons, Patrick Seale, Rexford S. Ahima, Doris A. Stoffers
Published 2017-07-01

Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance

by Alan C. Rupp, Margaret B. Allison, Justin C. Jones, Christa M. Patterson, Chelsea L. Faber, Nadejda Bozadjieva, Lora K. Heisler, Randy J. Seeley, David P. Olson, Martin G. Myers, Jr.
Published 2018-08-01

Continuous glucose monitoring reveals glycemic variability and hypoglycemia after vertical sleeve gastrectomy in rats

by Simon S. Evers, Ki-Suk Kim, Nadejda Bozadjieva, Alfor G. Lewis, Diana Farris, Matthew J. Sorensen, Youngsoo Kim, Steven E. Whitesall, Robert T. Kennedy, Daniel E. Michele, Randy J. Seeley, Darleen A. Sandoval
Published 2020-02-01

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

by Nadejda Bozadjieva-Kramer, Jae Hoon Shin, Yikai Shao, Ruth Gutierrez-Aguilar, Ziru Li, Kristy M. Heppner, Samuel Chiang, Sara G. Vargo, Katrina Granger, Darleen A. Sandoval, Ormond A. MacDougald, Randy J. Seeley
Published 2021-08-01

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

by Laurie L. Baggio, John R. Ussher, Brent A. McLean, Xiemin Cao, M. Golam Kabir, Erin E. Mulvihill, Alexandra S. Mighiu, Hangjun Zhang, Andreas Ludwig, Randy J. Seeley, Scott P. Heximer, Daniel J. Drucker
Published 2017-11-01

Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.

by Ji-Yeon Lee, Heike Muenzberg, Oksana Gavrilova, Jacquelyn A Reed, Darlene Berryman, Eneida C Villanueva, Gwendolyn W Louis, Gina M Leinninger, Stefano Bertuzzi, Randy J Seeley, Gertraud W Robinson, Martin G Myers, Lothar Hennighausen
Published 2008-01-01

Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation

by Danna M. Breen, Srinath Jagarlapudi, Anita Patel, Chang Zou, Stephanie Joaquim, Xiangping Li, Liya Kang, Jincheng Pang, Katherine Hales, Enida Ziso-Qejvanaj, Nicholas B. Vera, Donald Bennett, Tao He, Matthew Lambert, Kerry Kelleher, Zhidan Wu, Bei B. Zhang, Laura Lin, Randy J. Seeley, Olivier Bezy
Published 2021-06-01

Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity

by Anne-Marie C. Overstreet, Bernadette E. Grayson, Antonia Boger, Danika Bakke, Erin M. Carmody, Cayla E. Bales, Shirley C. Paski, Stephen F. Murphy, Christopher R. Dethlefs, Kara J. Shannon, Katie R. Adlaka, Claire E. Wolford, Vincent J. Campiti, Christina V. Raghunandan, Randy J. Seeley, David L. Boone
Published 2021-05-01

Dietary sugars, not lipids, drive hypothalamic inflammation

by Yuanqing Gao, Maximilian Bielohuby, Thomas Fleming, Gernot F. Grabner, Ewout Foppen, Wagner Bernhard, Mara Guzmán-Ruiz, Clarita Layritz, Beata Legutko, Erwin Zinser, Cristina García-Cáceres, Ruud M. Buijs, Stephen C. Woods, Andries Kalsbeek, Randy J. Seeley, Peter P. Nawroth, Martin Bidlingmaier, Matthias H. Tschöp, Chun-Xia Yi
Published 2017-08-01

Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation

by Silvana Obici, I. Jack Magrisso, Armen S. Ghazarian, Alireza Shirazian, Jonas R. Miller, Christine M. Loyd, Denovan P. Begg, Kimberly A. Krawczewski Carhuatanta, Michael K. Haas, Jon F. Davis, Stephen C. Woods, Darleen A. Sandoval, Randy J. Seeley, Laurie J. Goodyear, Emmanuel N. Pothos, Joram D. Mul
Published 2015-10-01

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

by Anders B. Klein, Trine S. Nicolaisen, Niels Ørtenblad, Kasper D. Gejl, Rasmus Jensen, Andreas M. Fritzen, Emil L. Larsen, Kristian Karstoft, Henrik E. Poulsen, Thomas Morville, Ronni E. Sahl, Jørn W. Helge, Jens Lund, Sarah Falk, Mark Lyngbæk, Helga Ellingsgaard, Bente K. Pedersen, Wei Lu, Brian Finan, Sebastian B. Jørgensen, Randy J. Seeley, Maximilian Kleinert, Bente Kiens, Erik A. Richter, Christoffer Clemmensen
Published 2021-02-01