Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis

by Brian T. O’Neill, Hans P.M.M. Lauritzen, Michael F. Hirshman, Graham Smyth, Laurie J. Goodyear, C. Ronald Kahn
Published 2015-05-01

Characterization of an acute muscle contraction model using cultured C2C12 myotubes.

by Yasuko Manabe, Shouta Miyatake, Mayumi Takagi, Mio Nakamura, Ai Okeda, Taemi Nakano, Michael F Hirshman, Laurie J Goodyear, Nobuharu L Fujii
Published 2012-01-01

Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting

by Christiano R.R. Alves, Tara L. MacDonald, Pasquale Nigro, Prerana Pathak, Michael F. Hirshman, Laurie J. Goodyear, Sarah J. Lessard
Published 2019-09-01

Exercise intensity regulates cytokine and klotho responses in men

by Roeland J. W. Middelbeek, Piryanka Motiani, Nina Brandt, Pasquale Nigro, Jia Zheng, Kirsi A. Virtanen, Kari K. Kalliokoski, Jarna C. Hannukainen, Laurie J. Goodyear
Published 2021-01-01

Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity

by Christie M. Penniman, Pablo A. Suarez Beltran, Gourav Bhardwaj, Taylor L. Junck, Jayashree Jena, Kennedy Poro, Michael F. Hirshman, Laurie J. Goodyear, Brian T. O'Neill
Published 2019-12-01

Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype

by Ana Barbara Alves-Wagner, Kristin I Stanford, Noah B Prince, Kawai So, Joram D Mul, Ercument Dirice, Michael F Hirshman, Rohit N Kulkarni, Laurie J Goodyear
Published 2020-04-01

JNK regulates muscle remodeling via myostatin/SMAD inhibition

by Sarah J. Lessard, Tara L. MacDonald, Prerana Pathak, Myoung Sook Han, Vernon G. Coffey, Johann Edge, Donato A. Rivas, Michael F. Hirshman, Roger J. Davis, Laurie J. Goodyear
Published 2018-08-01

Disconnecting Mitochondrial Content from Respiratory Chain Capacity in PGC-1-Deficient Skeletal Muscle

by Glenn C. Rowe, Ian S. Patten, Zsuzsanna K. Zsengeller, Riyad El-Khoury, Mitsuharu Okutsu, Sophia Bampoh, Nicole Koulisis, Caitlin Farrell, Michael F. Hirshman, Zhen Yan, Laurie J. Goodyear, Pierre Rustin, Zolt Arany
Published 2013-05-01

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

by Rhianna C. Laker, Joshua C. Drake, Rebecca J. Wilson, Vitor A. Lira, Bevan M. Lewellen, Karen A. Ryall, Carleigh C. Fisher, Mei Zhang, Jeffrey J. Saucerman, Laurie J. Goodyear, Mondira Kundu, Zhen Yan
Published 2017-09-01

Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue

by Adam C. Lehnig, Revati S. Dewal, Lisa A. Baer, Kathryn M. Kitching, Vitor Rosetto Munoz, Peter J. Arts, Devin A. Sindeldecker, Francis J. May, Hans P.M.M. Lauritzen, Laurie J. Goodyear, Kristin I. Stanford
Published 2019-01-01

Lipidomic Adaptations in White and Brown Adipose Tissue in Response to Exercise Demonstrate Molecular Species-Specific Remodeling

by Francis J. May, Lisa A. Baer, Adam C. Lehnig, Kawai So, Emily Y. Chen, Fei Gao, Niven R. Narain, Liubov Gushchina, Aubrey Rose, Andrea I. Doseff, Michael A. Kiebish, Laurie J. Goodyear, Kristin I. Stanford
Published 2017-02-01

l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

by Yusuke Adachi, Ana Luisa De Sousa-Coelho, Ikue Harata, Charlie Aoun, Sandra Weimer, Xu Shi, Karina N. Gonzalez Herrera, Hirokazu Takahashi, Chris Doherty, Yasushi Noguchi, Laurie J. Goodyear, Marcia C. Haigis, Robert E. Gerszten, Mary-Elizabeth Patti
Published 2018-11-01

Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

by Carles Lerin, Allison B. Goldfine, Tanner Boes, Manway Liu, Simon Kasif, Jonathan M. Dreyfuss, Ana Luisa De Sousa-Coelho, Grace Daher, Irini Manoli, Justin R. Sysol, Elvira Isganaitis, Niels Jessen, Laurie J. Goodyear, Kirk Beebe, Walt Gall, Charles P. Venditti, Mary-Elizabeth Patti
Published 2016-10-01

The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

by André L. Queiroz, Sarah J. Lessard, Amanda T. Ouchida, Hygor N. Araujo, Dawit A. Gonçalves, Dimitrius Santiago P. Simões Fróes Guimarães, Bruno G. Teodoro, Kawai So, Enilza M. Espreafico, Michael F. Hirshman, Luciane C. Alberici, Isis do Carmo Kettelhut, Laurie J. Goodyear, Leonardo R. Silveira
Published 2021-09-01

Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation

by Silvana Obici, I. Jack Magrisso, Armen S. Ghazarian, Alireza Shirazian, Jonas R. Miller, Christine M. Loyd, Denovan P. Begg, Kimberly A. Krawczewski Carhuatanta, Michael K. Haas, Jon F. Davis, Stephen C. Woods, Darleen A. Sandoval, Randy J. Seeley, Laurie J. Goodyear, Emmanuel N. Pothos, Joram D. Mul
Published 2015-10-01

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

by Farnaz Shamsi, Ruidan Xue, Tian Lian Huang, Morten Lundh, Yang Liu, Luiz O. Leiria, Matthew D. Lynes, Elena Kempf, Chih-Hao Wang, Satoru Sugimoto, Pasquale Nigro, Kathrin Landgraf, Tim Schulz, Yiming Li, Brice Emanuelli, Srinivas Kothakota, Lewis T. Williams, Niels Jessen, Steen Bønløkke Pedersen, Yvonne Böttcher, Matthias Blüher, Antje Körner, Laurie J. Goodyear, Moosa Mohammadi, C. Ronald Kahn, Yu-Hua Tseng
Published 2020-03-01

Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

by Christiano R.R. Alves, Willian das Neves, Ney R. de Almeida, Eric J. Eichelberger, Paulo R. Jannig, Vanessa A. Voltarelli, Gabriel C. Tobias, Luiz R.G. Bechara, Daniele de Paula Faria, Maria J.N. Alves, Lars Hagen, Animesh Sharma, Geir Slupphaug, José B.N. Moreira, Ulrik Wisloff, Michael F. Hirshman, Carlos E. Negrão, Gilberto de Castro Jr, Roger Chammas, Kathryn J. Swoboda, Jorge L. Ruas, Laurie J. Goodyear, Patricia C. Brum
Published 2020-09-01