Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase1

We discovered a nuclear receptor element in the FAS promoter consisting of an inverted repeat spaced by one nucleotide (IR-1) and located 21 bases downstream of a direct repeat sequenced by 4 nucleotides (DR-4) oxysterol liver X receptor response element. An IR-1 is present in promoters of several g...

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Bibliographic Details
Main Authors: Karen E. Matsukuma, Mary K. Bennett, Jiansheng Huang, Li Wang, Gregorio Gil, Timothy F. Osborne
Format: Article
Language:English
Published: Elsevier 2006-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520432675