DNA Methylation as a Marker of Body Shape in Premenopausal Women

by Adeline Divoux, Alexey Eroshkin, Edina Erdos, Katalin Sandor, Timothy F. Osborne, Steven R. Smith
Published 2021-07-01

Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase1

by Karen E. Matsukuma, Mary K. Bennett, Jiansheng Huang, Li Wang, Gregorio Gil, Timothy F. Osborne
Published 2006-12-01

Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: primary outcomes

by Adeline Divoux, Katalin Sandor, Dora Bojcsuk, Amlan Talukder, Xiaoman Li, Balint L. Balint, Timothy F. Osborne, Steven R. Smith
Published 2018-11-01

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression[S]

by Laurent Vergnes, Robert G. Chin, Thomas de Aguiar Vallim, Loren G. Fong, Timothy F. Osborne, Stephen G. Young, Karen Reue
Published 2016-03-01

Sterol and fatty acid regulatory pathways in a Giardia lamblia-derived promoter

by Tilla S. Worgall, Sara R. Davis-Hayman, Marissa M. Magana, Peter M. Oelkers, Fernando Zapata, Rebecca A. Juliano, Timothy F. Osborne, Theodore E. Nash, Richard J. Deckelbaum
Published 2004-05-01

Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

by Yohei Abe, Yosuke Fujiwara, Hiroki Takahashi, Yoshihiro Matsumura, Tomonobu Sawada, Shuying Jiang, Ryo Nakaki, Aoi Uchida, Noriko Nagao, Makoto Naito, Shingo Kajimura, Hiroshi Kimura, Timothy F. Osborne, Hiroyuki Aburatani, Tatsuhiko Kodama, Takeshi Inagaki, Juro Sakai
Published 2018-04-01

T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

by Kathleen Smith, Elnaz Karimian Azari, Traci E. LaMoia, Tania Hussain, Veronika Vargova, Katalin Karolyi, Paula P. Veldhuis, Juan Pablo Arnoletti, Sebastian G. de la Fuente, Richard E. Pratley, Timothy F. Osborne, George A. Kyriazis
Published 2018-11-01

Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis

by Chia-Chi C. Key, Mingxia Liu, C. Lisa Kurtz, Soonkyu Chung, Elena Boudyguina, Timothy A. Dinh, Alexander Bashore, Peter E. Phelan, Barry I. Freedman, Timothy F. Osborne, Xuewei Zhu, Lijun Ma, Praveen Sethupathy, Sudha B. Biddinger, John S. Parks
Published 2017-06-01

Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.

by Yun-Seung Jeong, Deokhoon Kim, Yong Seok Lee, Ha-Jung Kim, Jung-Youn Han, Seung-Soon Im, Hansook Kim Chong, Je-Keun Kwon, Yun-Ho Cho, Woo Kyung Kim, Timothy F Osborne, Jay D Horton, Hee-Sook Jun, Yong-Ho Ahn, Sung-Min Ahn, Ji-Young Cha
Published 2011-01-01

Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue

by Jae-Ho Lee, Younghoon Go, Do-Young Kim, Sun Hee Lee, Ok-Hee Kim, Yong Hyun Jeon, Taeg Kyu Kwon, Jae-Hoon Bae, Dae-Kyu Song, Im Joo Rhyu, In-Kyu Lee, Minho Shong, Byung-Chul Oh, Christopher Petucci, Jeen-Woo Park, Timothy F. Osborne, Seung-Soon Im
Published 2020-02-01

Correction: Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue

by Jae-Ho Lee, Younghoon Go, Do-Young Kim, Sun Hee Lee, Ok-Hee Kim, Yong Hyun Jeon, Taeg Kyu Kwon, Jae-Hoon Bae, Dae-Kyu Song, Im Joo Rhyu, In-Kyu Lee, Minho Shong, Byung-Chul Oh, Christopher Petucci, Jeen-Woo Park, Timothy F. Osborne, Seung-Soon Im
Published 2020-06-01

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance

by Sheila R. Costford, Bram Brouwers, Meghan E. Hopf, Lauren M. Sparks, Mauro Dispagna, Ana P. Gomes, Heather H. Cornnell, Chris Petucci, Peter Phelan, Hui Xie, Fanchao Yi, Glenn A. Walter, Timothy F. Osborne, David A. Sinclair, Randall L. Mynatt, Julio E. Ayala, Stephen J. Gardell, Steven R. Smith
Published 2018-01-01

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

by Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore, Bina Albuquerque, Allan Reyes, Yuji Shi, Rob Moccia, Emily Cokorinos, Matthew Peloquin, Mara Monetti, Jason Barricklow, Eliza Bollinger, Brennan K. Smith, Emily A. Day, Chuong Nguyen, Kieran F. Geoghegan, John M. Kreeger, Alan Opsahl, Jessica Ward, Amit S. Kalgutkar, David Tess, Lynne Butler, Norimitsu Shirai, Timothy F. Osborne, Gregory R. Steinberg, Morris J. Birnbaum, Kimberly O. Cameron, Russell A. Miller
Published 2018-05-01