Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria

Gram-negative carbapenem-resistant bacteria are a major threat to global health. The use of genome-wide screening approaches to probe for genes or mutations enabling resistance can lead to identification of molecular markers for diagnostics applications. We describe an approach called Mut-Seq that c...

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Bibliographic Details
Main Authors: Jessica Y. El Khoury, Alexandra Maure, Hélène Gingras, Philippe Leprohon, Marc Ouellette
Format: Article
Language:English
Published: American Society for Microbiology 2019-11-01
Series:mSystems
Subjects:
Online Access:https://doi.org/10.1128/mSystems.00465-19