Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria
Gram-negative carbapenem-resistant bacteria are a major threat to global health. The use of genome-wide screening approaches to probe for genes or mutations enabling resistance can lead to identification of molecular markers for diagnostics applications. We describe an approach called Mut-Seq that c...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-11-01
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Series: | mSystems |
Subjects: | |
Online Access: | https://doi.org/10.1128/mSystems.00465-19 |