High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel.

High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel.

<h4>Background</h4>Zika virus (ZIKV) and Dengue virus (DENV) are often co-endemic. The high protein-sequence homology of flaviviruses renders IgG induced by and directed against them highly cross-reactive against their antigen(s), as observed on a large set of sera, leading to poorly rel...

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Bibliographic Details
Main Authors: Jessica Denis, Sarah Attoumani, Patrick Gravier, Bernard Tenebray, Annabelle Garnier, Sébastien Briolant, Franck de Laval, Véronique Chastres, Gilda Grard, Isabelle Leparc-Goffart, Bruno Coutard, Cyril Badaut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007747

Internet

https://doi.org/10.1371/journal.pntd.0007747

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