Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells

Regulatory T cells (Tregs) are potent suppressors of immune responses and are currently being clinically tested for their potential to stop or control undesired immune responses in autoimmunity, hematopoietic stem cell transplantation, and solid organ transplantation. Current clinical approaches aim...

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Bibliographic Details
Main Authors: Nicholas A. J. Dawson, Jens Vent-Schmidt, Megan K. Levings
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01460/full