Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.

In many situations, 3D cell cultures mimic the natural organization of tissues more closely than 2D cultures. Conventional methods for phenotyping such 3D cultures use either single or multiple simple parameters based on morphology and fluorescence staining intensity. However, due to their simplicit...

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Bibliographic Details
Main Authors: Zi Di, Maarten J D Klop, Vasiliki-Maria Rogkoti, Sylvia E Le Dévédec, Bob van de Water, Fons J Verbeek, Leo S Price, John H N Meerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4188701?pdf=render