Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects

Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects

Infection by the Trypanosoma cruzi parasite causes Chagas disease and triggers multiple immune mechanisms in the host to combat the pathogen. Chagas disease has a variable clinical presentation and progression, producing in the chronic phase a fragile balance between the host immune response and par...

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Bibliographic Details
Main Authors: Inmaculada Gómez, M. Carmen Thomas, Génesis Palacios, Adriana Egui, Bartolomé Carrilero, Marina Simón, Basilio Valladares, Manuel Segovia, Emma Carmelo, Manuel Carlos López
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
chronic Chagas disease
Trypanosoma cruzi
transcriptional profiling
high-throughput RT-qPCR
immunological pathway
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.722984/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.722984/full

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