NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

Abstract This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome...

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Bibliographic Details
Main Authors: Heidi M. Britton, Adrian B. Levine, Yaoqing Shen, Karen Mungall, Jonathan Serrano, Matija Snuderl, Erin Pleasance, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh, Rebecca Deyell, Stephen Yip, Sylvia Cheng, Chris Dunham
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical Case Reports
Online Access:https://doi.org/10.1002/ccr3.3804

Internet

https://doi.org/10.1002/ccr3.3804

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