Snake and Spider Toxins Induce a Rapid Recovery of Function of Botulinum Neurotoxin Paralysed Neuromuscular Junction

Snake and Spider Toxins Induce a Rapid Recovery of Function of Botulinum Neurotoxin Paralysed Neuromuscular Junction

Botulinum neurotoxins (BoNTs) and some animal neurotoxins (β-Bungarotoxin, β-Btx, from elapid snakes and α-Latrotoxin, α-Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients. However, their mechanism of action is di...

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Bibliographic Details
Main Authors: Elisa Duregotti, Giulia Zanetti, Michele Scorzeto, Aram Megighian, Cesare Montecucco, Marco Pirazzini, Michela Rigoni
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Toxins
Subjects:
botulinum neurotoxins
animal neurotoxins
nerve terminals degeneration
mouse
DAS assay
paralysis
neuroexocytosis
Online Access:http://www.mdpi.com/2072-6651/7/12/4887

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http://www.mdpi.com/2072-6651/7/12/4887

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