Immunization against a saccharide epitope accelerates clearance of experimental gonococcal infection.

Immunization against a saccharide epitope accelerates clearance of experimental gonococcal infection.

The emergence of ceftriaxone-resistant strains of Neisseria gonorrhoeae may herald an era of untreatable gonorrhea. Vaccines against this infection are urgently needed. The 2C7 epitope is a conserved oligosaccharide (OS) structure, a part of lipooligosaccharide (LOS) on N gonorrhoeae. The epitope is...

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Bibliographic Details
Main Authors: Sunita Gulati, Bo Zheng, George W Reed, Xiaohong Su, Andrew D Cox, Frank St Michael, Jacek Stupak, Lisa A Lewis, Sanjay Ram, Peter A Rice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3757034?pdf=render

Internet

http://europepmc.org/articles/PMC3757034?pdf=render

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