Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine

by Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram, Peter A. Rice
Published 2019-02-01

The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein.

by Peter T Beernink, Jutamas Shaughnessy, Rolando Pajon, Emily M Braga, Sanjay Ram, Dan M Granoff
Published 2012-01-01

The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.

by Lisa A Lewis, Jutamas Ngampasutadol, Ruth Wallace, Jane E A Reid, Ulrich Vogel, Sanjay Ram
Published 2010-07-01

High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy.

by Paul Brent Ferrell, Kirsten Elizabeth Diggins, Hannah Grace Polikowsky, Sanjay Ram Mohan, Adam C Seegmiller, Jonathan Michael Irish
Published 2016-01-01

Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing

by Maisem Laabei, Maisem Laabei, Lucie Colineau, Serena Bettoni, Karolina Maziarz, David Ermert, Kristian Riesbeck, Sanjay Ram, Anna M. Blom
Published 2020-09-01

The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus

by David Ermert, David Ermert, Maisem Laabei, Antonin Weckel, Matthias Mörgelin, Martin Lundqvist, Lars Björck, Sanjay Ram, Sara Linse, Anna M. Blom
Published 2019-06-01

Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae

by Jutamas Shaughnessy, Y Tran, Bo Zheng, Rosane B. DeOliveira, Sunita Gulati, Wen-Chao Song, James M. Maclean, Keith L. Wycoff, Sanjay Ram
Published 2020-10-01

Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors.

by David Ermert, Jutamas Shaughnessy, Thorsten Joeris, Jakub Kaplan, Catherine J Pang, Evelyn A Kurt-Jones, Peter A Rice, Sanjay Ram, Anna M Blom
Published 2015-07-01

Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission.

by Thomas Hart, Ngoc Thien Thu Nguyen, Nancy A Nowak, Fuming Zhang, Robert J Linhardt, Maria Diuk-Wasser, Sanjay Ram, Peter Kraiczy, Yi-Pin Lin
Published 2018-05-01

Evolution of the exclusively human pathogen Neisseria gonorrhoeae: Human‐specific engagement of immunoregulatory Siglecs

by Corinna S. Landig, Ashley Hazel, Benjamin P. Kellman, Jerry J. Fong, Flavio Schwarz, Sarika Agarwal, Nissi Varki, Paola Massari, Nathan E. Lewis, Sanjay Ram, Ajit Varki
Published 2019-02-01

Immunization against a saccharide epitope accelerates clearance of experimental gonococcal infection.

by Sunita Gulati, Bo Zheng, George W Reed, Xiaohong Su, Andrew D Cox, Frank St Michael, Jacek Stupak, Lisa A Lewis, Sanjay Ram, Peter A Rice
Published 2013-01-01

Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae

by Serena Bettoni, Karolina Maziarz, M Rhia L Stone, Mark A T Blaskovich, Jan Potempa, Jan Potempa, Maria Luiza Bazzo, Magnus Unemo, Sanjay Ram, Anna M. Blom
Published 2021-09-01

Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine

by Sunita Gulati, Michael W. Pennington, Andrzej Czerwinski, Darrick Carter, Bo Zheng, Nancy A. Nowak, Rosane B. DeOliveira, Jutamas Shaughnessy, George W. Reed, Sanjay Ram, Peter A. Rice
Published 2019-11-01

Candida albicans Factor H Binding Molecule Hgt1p – A Low Glucose-Induced Transmembrane Protein Is Trafficked to the Cell Wall and Impairs Phagocytosis and Killing by Human Neutroph...

by Samyr Kenno, Cornelia Speth, Günter Rambach, Ulrike Binder, Sneha Chatterjee, Rita Caramalho, Hubertus Haas, Cornelia Lass-Flörl, Jutamas Shaughnessy, Sanjay Ram, Neil A. R. Gow, Dorothea Orth-Höller, Reinhard Würzner
Published 2019-01-01

Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system.

by Thomas M Hart, Alan P Dupuis, Danielle M Tufts, Anna M Blom, Simon R Starkey, Ryan O M Rego, Sanjay Ram, Peter Kraiczy, Laura D Kramer, Maria A Diuk-Wasser, Sergios-Orestis Kolokotronis, Yi-Pin Lin
Published 2021-07-01

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody.

by Sunita Gulati, Frank J Beurskens, Bart-Jan de Kreuk, Marcel Roza, Bo Zheng, Rosane B DeOliveira, Jutamas Shaughnessy, Nancy A Nowak, Ronald P Taylor, Marina Botto, Xianbao He, Robin R Ingalls, Trent M Woodruff, Wen-Chao Song, Janine Schuurman, Peter A Rice, Sanjay Ram
Published 2019-06-01

Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics.

by Sunita Gulati, Ian C Schoenhofen, Dennis M Whitfield, Andrew D Cox, Jianjun Li, Frank St Michael, Evgeny V Vinogradov, Jacek Stupak, Bo Zheng, Makoto Ohnishi, Magnus Unemo, Lisa A Lewis, Rachel E Taylor, Corinna S Landig, Sandra Diaz, George W Reed, Ajit Varki, Peter A Rice, Sanjay Ram
Published 2015-12-01