Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)

The aryl hydrocarbon receptor (AhR) was first identified as the intracellular protein that bound and mediated the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and dioxin-like compounds (DLCs). Subsequent studies show that the AhR plays an important role in maintaining cellular...

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Bibliographic Details
Main Authors: Stephen Safe, Un-ho Jin, Hyejin Park, Robert S. Chapkin, Arul Jayaraman
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
AhR
Online Access:https://www.mdpi.com/1422-0067/21/18/6654