Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we measured the activation dynamics of the signal t...

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Bibliographic Details
Main Authors: Julien Dubrulle, Benjamin M Jordan, Laila Akhmetova, Jeffrey A Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, Alexander F Schier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
morphogen gradient
signal transduction
transcription rate
DNA binding affinity
Online Access:https://elifesciences.org/articles/05042

Internet

https://elifesciences.org/articles/05042

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