RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening.

BACKGROUND: The possible emergence of resistance to the only available drug for schistosomiasis spurs drug discovery that has been recently incentivized by the availability of improved transcriptome and genome sequence information. Transient RNAi has emerged as a straightforward and important techni...

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Bibliographic Details
Main Authors: Saša Stefanić, Jan Dvořák, Martin Horn, Simon Braschi, Daniel Sojka, Debbie S Ruelas, Brian Suzuki, Kee-Chong Lim, Stephanie D Hopkins, James H McKerrow, Conor R Caffrey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2957409?pdf=render