Regulatory network changes between cell lines and their tissues of origin

Regulatory network changes between cell lines and their tissues of origin

Abstract Background Cell lines are an indispensable tool in biomedical research and often used as surrogates for tissues. Although there are recognized important cellular and transcriptomic differences between cell lines and tissues, a systematic overview of the differences between the regulatory pr...

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Bibliographic Details
Main Authors: Camila M. Lopes-Ramos, Joseph N. Paulson, Cho-Yi Chen, Marieke L. Kuijjer, Maud Fagny, John Platig, Abhijeet R. Sonawane, Dawn L. DeMeo, John Quackenbush, Kimberly Glass
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Subjects:
Regulatory networks
Transcriptome
GTEx
Lymphoblastoid cell lines
Fibroblast cell lines
Online Access:http://link.springer.com/article/10.1186/s12864-017-4111-x

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http://link.springer.com/article/10.1186/s12864-017-4111-x

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