Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue.

Tar DNA Binding Protein-43 (TDP-43) is a principle component of inclusions in many cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP-43 resides predominantly in the nucleus, but in affected areas of ALS and FTLD-U central nervous system, TDP-43 is aberr...

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Bibliographic Details
Main Authors: Liqun Liu-Yesucevitz, Aylin Bilgutay, Yong-Jie Zhang, Tara Vanderweyde, Allison Citro, Tapan Mehta, Nava Zaarur, Ann McKee, Robert Bowser, Michael Sherman, Leonard Petrucelli, Benjamin Wolozin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2952586?pdf=render