Micropatterned hydrogenated amorphous carbon guides mesenchymal stem cells towards neuronal differentiation

Micropatterned hydrogenated amorphous carbon guides mesenchymal stem cells towards neuronal differentiation

This study investigated how the design of surface topography may stimulate stem cell differentiation towards a neural lineage. To this end, hydrogenated amorphous carbon (a-C:H) groove topographies with width/spacing ridges ranging from 80/40µm, 40/30µm and 30/20µm and depth of 24 nm were used as a...

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Bibliographic Details
Main Authors: F D’Angelo, I Armentano, S Mattioli, L Crispoltoni, R Tiribuzi, GG Cerulli, CA Palmerini, JM Kenny, S Martino, A Orlacchio
Format: Article
Language:English
Published: AO Research Institute Davos 2010-10-01
Series:European Cells & Materials
Subjects:
Biological response
cell/protein-material interactions
biomaterial surfaces
tissue engineering
regenerative medicine
cytoskeleton
stem cell differentiation
Online Access:http://www.ecmjournal.org/journal/papers/vol020/pdf/v020a19.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol020/pdf/v020a19.pdf

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