Proteomics Approaches to Identify Tumor Antigen Directed Autoantibodies as Cancer Biomarkers

The identification of autoantibodies to tumor cell proteins by proteomics approaches has great potential impact on cancer biomarker discovery. The humoral immune response represents a form of biological amplification of signals that are otherwise weak due to very low concentrations of antigen, espec...

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Bibliographic Details
Main Authors: Yuji Imafuku, Gilbert S. Omenn, Samir Hanash
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2004/829450