Regulatory variation at glypican-3 underlies a major growth QTL in mice.

The genetic basis of variation in complex traits remains poorly understood, and few genes underlying variation have been identified. Previous work identified a quantitative trait locus (QTL) responsible for much of the response to selection on growth in mice, effecting a change in body mass of appro...

Full description

Bibliographic Details
Main Authors: Fiona Oliver, Julian K Christians, Xiaojun Liu, Susan Rhind, Vinesh Verma, Claire Davison, Steve D M Brown, Paul Denny, Peter D Keightley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1073695?pdf=render