Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.
Voltage-dependent K(+) (Kv) channels gate open in response to the membrane voltage. To further our understanding of how cell membrane voltage regulates the opening of a Kv channel, we have studied the protein interfaces that attach the voltage-sensor domains to the pore. In the crystal structure, th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-03-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC2650729?pdf=render |