Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites
Despite functional optimisation during evolution of parasitism, most members of a calcium dependent protein kinase (CDPK) family show genetic redundancy in Plasmodium. Here, the authors screen 294 genetic interactions among protein kinases in Plasmodium and show how some CDPKs functionally interact...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06733-w |