CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target

CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target

Abstract CARF (Collaborator of ARF)/CDKN2AIP was discovered as a novel ARF-binding protein. It has been established as an essential cell survival, p53-, and cell proliferation-regulatory protein. Although a moderate upregulation of CARF caused growth arrest and senescence, its excessively enriched l...

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Bibliographic Details
Main Authors: Rajkumar S. Kalra, Anupama Chaudhary, A-Rum Yoon, Priyanshu Bhargava, Amr Omar, Sukant Garg, Chae-Ok Yun, Sunil C. Kaul, Renu Wadhwa
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-018-0048-4

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https://doi.org/10.1038/s41389-018-0048-4

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