Insight into the structure of amyloid fibrils from the analysis of globular proteins.
The conversion from soluble states into cross-beta fibrillar aggregates is a property shared by many different proteins and peptides and was hence conjectured to be a generic feature of polypeptide chains. Increasing evidence is now accumulating that such fibrillar assemblies are generally character...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1698942?pdf=render |