HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.

Reversible protein acetylation provides a central mechanism for controlling gene expression and cellular signaling events. It is governed by the antagonistic commitment of two enzymes families: the histone acetyltransferases (HATs) and the histone deacetylases (HDACs). HDAC4, like its class IIa coun...

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Bibliographic Details
Main Authors: Michal Mielcarek, Tamara Seredenina, Matthew P Stokes, Georgina F Osborne, Christian Landles, Linda Inuabasi, Sophie A Franklin, Jeffrey C Silva, Ruth Luthi-Carter, Vahri Beaumont, Gillian P Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3838388?pdf=render