DNA methylation is associated with lung function in never smokers

DNA methylation is associated with lung function in never smokers

Abstract Background Active smoking is the main risk factor for COPD. Here, epigenetic mechanisms may play a role, since cigarette smoking is associated with differential DNA methylation in whole blood. So far, it is unclear whether epigenetics also play a role in subjects with COPD who never smoked....

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Bibliographic Details
Main Authors: Maaike de Vries, Ivana Nedeljkovic, Diana A. van der Plaat, Alexandra Zhernakova, Lies Lahousse, Guy G. Brusselle, BIOS Consortium, Najaf Amin, Cornelia M. van Duijn, Judith M. Vonk, H. Marike Boezen
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Respiratory Research
Subjects:
DNA methylation
Never smokers
FEV1/FVC
EWAS
COPD
Online Access:https://doi.org/10.1186/s12931-019-1222-8

Internet

https://doi.org/10.1186/s12931-019-1222-8

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