DNA methylation is associated with lung function in never smokers
Abstract Background Active smoking is the main risk factor for COPD. Here, epigenetic mechanisms may play a role, since cigarette smoking is associated with differential DNA methylation in whole blood. So far, it is unclear whether epigenetics also play a role in subjects with COPD who never smoked....
Main Authors: | Maaike de Vries, Ivana Nedeljkovic, Diana A. van der Plaat, Alexandra Zhernakova, Lies Lahousse, Guy G. Brusselle, BIOS Consortium, Najaf Amin, Cornelia M. van Duijn, Judith M. Vonk, H. Marike Boezen |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-019-1222-8 |
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