Intracerebral Transplantation of Differentiated Human Embryonic Stem Cells to Hemiparkinsonian Monkeys

To explore stem cell therapy for Parkinson's disease (PD), three adult rhesus monkeys were first rendered hemiparkinsonian by unilateral intracarotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) infusion. Five months postinfusion, they were given MRI-guided stereotaxic intrastriatal and...

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Bibliographic Details
Main Authors: Marina E. Emborg M.D., Ph.D., Zhijian Zhang, Valerie Joers, Kevin Brunner, Viktorya Bondarenko, Sachiko Ohshima, Su-Chun Zhang
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X647144