Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

Summary: Several distinct differentiation protocols for deriving pancreatic progenitors (PPs) from human pluripotent stem cells have been described, but it remains to be shown how similar the PPs are across protocols and how well they resemble their in vivo counterparts. Here, we evaluated three dif...

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Bibliographic Details
Main Authors: Agata Wesolowska-Andersen, Rikke Rejnholdt Jensen, Marta Pérez Alcántara, Nicola L. Beer, Claire Duff, Vibe Nylander, Matthew Gosden, Lorna Witty, Rory Bowden, Mark I. McCarthy, Mattias Hansson, Anna L. Gloyn, Christian Honore
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119304138

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http://www.sciencedirect.com/science/article/pii/S2213671119304138

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