CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

Summary: Mutations and deletions of polycomb repressive complex (PRC) components are increasingly recognized to affect tumor biology in a range of cancers. However, little is known about how genetic alterations of PRC-interacting molecules such as the core binding factor (CBF) complex influence poly...

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Bibliographic Details
Main Authors: Gaëlle Cordonnier, Amit Mandoli, Nicolas Cagnard, Guillaume Hypolite, Ludovic Lhermitte, Els Verhoeyen, Vahid Asnafi, Niall Dillon, Elizabeth Macintyre, Joost H.A. Martens, Jonathan Bond
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316766