Discovery of Pyrrolidine-2,3-diones as Novel Inhibitors of <i>P. aeruginosa</i> PBP3

Discovery of Pyrrolidine-2,3-diones as Novel Inhibitors of <i>P. aeruginosa</i> PBP3

The alarming threat of the spread of multidrug resistant bacteria currently leaves clinicians with very limited options to combat infections, especially those from Gram-negative bacteria. Hence, innovative strategies to deliver the next generation of antibacterials are urgently needed. Penicillin bi...

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Bibliographic Details
Main Authors: Arancha López-Pérez, Stefan Freischem, Immanuel Grimm, Oliver Weiergräber, Andrew J. Dingley, María Pascual López-Alberca, Herbert Waldmann, Waldemar Vollmer, Kamal Kumar, Cuong Vuong
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antibiotics
Subjects:
PBPs
<i>P. aeruginosa</i>
penicillin binding proteins
HTS
β-lactams
multi-drug resistance
Online Access:https://www.mdpi.com/2079-6382/10/5/529

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https://www.mdpi.com/2079-6382/10/5/529

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