Inhibition and Facilitation by Pimobendan, a Calcium Sensitizer, of Catecholamine Secretion From Bovine Adrenal Chromaffin Cells
The effects of pimobendan, a Ca2+ sensitizer with inhibitory action against cyclic-GMP-inhibited phosphodiesterase (PDE-III), on catecholamine (CA) secretion were studied in bovine adrenal chromaffin cells. In intact cells, pimobendan (10 – 100 μM) inhibited CA secretion stimulated by acetylcholine...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2003-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319327367 |